Applications

Biochemical and
Immunochemical properties

  • Muñoz SM, Vallejos-Baccelliere G, Manubens A, Salazar ML, Nascimento AFZ, Tapia-Reyes P, Meneses C, Ambrosio ALB, Becker MI, Guixé V, Castro-Fernandez V. Structural insights into a functional unit from an immunogenic mollusk hemocyanin. Structure. 32(6):812-823. (2024). e4. doi: 10.1016/j.str.2024.02.018.
  • Paquet M, Fujii T, Moynier F. Copper isotope composition of hemocyanin. J Trace Elem Med Biol. 71:126967 (2022). doi: 10.1016/j.jtemb.2022.126967.
  • González A, Nova E, Del Campo M, Manubens A, De Ioannes A, Ferreira J, Becker MI. The oxygen-binding properties of hemocyanin from the mollusk Concholepas concholepas. Biochim Biophys Acta Proteins Proteom. 1865:1746-1757 (2917). doi: 10.1016/j.bbapap.2017.08.017.
  • Arancibia S, Del Campo M, Nova E, Salazar F, Becker MI. Enhanced structural stability of Concholepas hemocyanin increases its immunogenicity and maintains its non-specific immunostimulatory effects. Eur J Immunol. 42: 688-699. (2012). doi: 10.1002/eji.201142011.
  • Manubens A, Salazar F, Haussmann D, Figueroa J, Del Campo M, Pinto JM, Huaquín L, Venegas A, Becker MI. Concholepas hemocyanin biosynthesis takes place in the hepatopancreas, with hemocytes being involved in its metabolism. Cell Tissue Res. 342: 423-435 (2010). doi: 10.1007/s00441-010-1057-6.
  • Idakieva K., Nikolov P., Chakarska I., Genov N., Shnyrov V.L. Spectroscopic properties and conformational stability of Concholepas concholepas hemocyanin. J Fluoresc. DOI 10.1007/s10895-008-0338-x (2008). doi: 10.1007/s10895-008-0338-x.
  • Leyton p., Lizama-Vergara P.A., Campos-Vallette M., Becker M.I., Clavijo E., Córdova Reyes I., Vera M., Jeréz C.A. Surface enhanced Raman spectrum of nanometric molecular systems. J. Chil. Chem. Soc., 50: 725-730 (2005). doi.org/10.4067/S0717-97072005000400014.
  • De Ioannes P, Moltedo B, Oliva H, Pacheco R, De Ioannes A. E., Becker M.I Hemocyanin of the molluskan Concholepas concholepas exhibits an unusual heterodecameric array of subunits. J. Biological Chemistry 279: 26134-26142 (2004). doi: 10.1074/jbc.M400903200.
  • Oliva H, Moltedo B, De Ioannes P, Faunes F, De Ioannes AE, Becker MI. Monoclonal antibodies to molluskan hemocyanin from Concholepas concholepas demonstrate common and specific epitopes among subunits. Hybridoma and Hybridomics 21: 365 – 374 (2002). doi: 10.1089/153685902761022715.