Product developed and commercialized by Thermo Scientific catalog number.

A robust, inexpensive alternative to KLH Blue Carrier Protein is a purified preparation of Concholepas concholepashemocyanin (CCH). The large protein exhibits most of the same immunogenic properties as the popular carrier protein, keyhole limpet hemocyanin (KLH). However, its significantly better solubility provides greater flexibility in immunogen preparation protocols by allowing a broader range of buffer and pH conditions for coupling peptides, proteins and other haptens using classical crosslinkers such as glutaraldehyde, Sulfo-SMCC and EDC.

Description:
Thermo Scientific enables conjugation of sulfhydryl-containing peptide antigens to this soluble immunogenic carrier protein for immunization and effective antibody production.

Features of ImjectMaleimide-Activated Blue® Carrier Protein:

Optimized activation
Specifications require that each lot is activated with more than 400 moles of sulhydryl-reactive maleimide per mole of carrier, ensuring consistently high levels of conjugation

Sulfhydryl-reactive
Engineered for conjugating cysteine-containing peptide antigens to make effective immunogens for high-titer antibody production

Simple, rapid procedure
Complete the hapten-carrier conjugation reaction in two hours to yield sufficient immunogen for several injections and booster immunizations of host animals

High-quality carrier protein
Blue Carrier Protein is ultrapure Concholepas concholepashemocyanin (CCH) prepared from molluscan hemolymph

Highly immunogenic and soluble
CCH has a high molecular mass that elicits a stronger immune response than BSA or ovalbumin

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